5 Essential Elements For cees dekker
5 Essential Elements For cees dekker
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‘The second is nanopores, that's our oldest line of exploration and which has now resulted in DNA sequencers based on nanopores. We pull specific DNA strands via a nanopore and will then read from the nucleotide sequence. Incredibly a short while ago, we even managed to examine out only one protein for The very first time applying This system. But this line of analysis is not simply about producing equipment, but in addition about real biological questions.
Human Rad51 filaments on double- and one-stranded DNA: correlating normal and irregular varieties with recombination function.
‘It absolutely was just a make a difference of picking up a reserve on mobile biology and starting to browse. I'd come from a world of ultra-high vacuums, cryostats and quantum phenomena, and now I had been Doing work at room temperature with molecular biology kits.
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
That may be a dream of mine and we established to operate having a mouth watering dose of naivety. This really is something which will most likely generate breathtaking ends in the longer phrase, but that doesn't make any difference. You should not only want to work about the thoughts of tomorrow, but in addition over the concerns in the working day just after tomorrow.’
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of just one wire bridging two electrodes
What distinguishes biology from chemistry is that these elements together make up a residing system. The trick of mentioned life, I feel, lies inside the interactions, the interaction of Individuals molecules. The massive query with regard to the origin of life remains unanswered. https://www.ceesdekker.net How did we ever evolve from very simple molecules to the exceptionally sophisticated techniques we see now? We have no idea. I would like to work on These types of huge, open up concerns.’
Nanopores characterize a chic and functional Resource to evaluate solitary molecules. We analysis novel detection modes with reliable-condition nanopores along with different approaches to measure proteins with nanopores. Projects encompass the subsequent:
2003, shown the 1st biosensors manufactured from a carbon nanotube; resolved the composition and system of DNA fix proteins; and discovery of a brand new technique for fabricating good-condition nanopores for DNA translocation
one). The current–voltage curves showed sizeable modulations with gate voltage, even at area temperature, which was according to band bending within a ~0.six eV bandgap semiconducting nanotube. These knowledge also confirmed that the conductance may very well be modulated by six orders of magnitude by transforming the gate voltage. The results of this do the job — a space-temperature transistor constructed from just one carbon nanotube molecule — ended up published in Nature in May well 1998.
FtsZ treadmilling is important for Z-ring condensation and septal constriction initiation in bacterial mobile division
Cees Dekker is Distinguished College Professor at TU Delft. Properly trained to be a physicist, he pioneered nanotechnology with many discoveries on carbon nanotubes in the nineteen nineties. Considering the fact that 2000, he moved to one-molecule biophysics and nanobiology. His latest exploration concentrates on (i) nanopores for protein sequencing; (ii) chromosome construction, particularly SMC motor protein; and (iii) building a living artificial mobile from lifeless molecules. Dekker is undoubtedly an elected member in the KNAW and fellow for the APS and also the IOP.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij achieved enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart structure in 2005. (nl)